Recombinant UBQLN4 抗体 (AA 2-601)
Quick Overview for Recombinant UBQLN4 抗体 (AA 2-601) (ABIN7455161)
抗原
See all UBQLN4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 2-601
-
原理
- Rabbit anti-UBQLN4/CIP75/Ubiquilin 4 Recombinant Monoclonal Antibody [BLR145J]
-
免疫原
- residues 2-601 (full length)
-
亚型
- IgG
-
-
anti-Ubiquilin 4 (UBQLN4) (AA 300-390) antibody
UBQLN4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (AA 287-336) antibodyUBQLN4 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 犬, Pig, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (Middle Region) antibodyUBQLN4 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠, 斑马鱼, 犬, Pig, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (AA 201-250) antibodyUBQLN4 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (N-Term) antibodyUBQLN4 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 20 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
-
限制
- 仅限研究用
-
-
-
浓度
- 50 μg/mL
-
缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- UBQLN4 (Ubiquilin 4 (UBQLN4))
-
别名
- UBQLN4/CIP75/Ubiquilin 4
-
背景
- Background: Ubiquilin-4 (UBQLN4) plays a role in the regulation of protein degradation via the ubiquitin-proteasome system (UPS). It mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. UBQLN4 Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). It acts as an adapter protein that recruits UBQLN1 to the autophagy machinery and mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205) [taken from NCBI Entrez Gene (Gene ID: 56893)].
-
基因ID
- 56893
-
NCBI登录号
- NP_064516
-
UniProt
- Q9NRR5
抗原
-
