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Recombinant SMAD4 抗体 (AA 1-50)

This anti-SMAD4 antibody is a 兔 单克隆 antibody detecting SMAD4 in WB, IP, ICC, FACS 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7455159
发货至: 中国

Quick Overview for Recombinant SMAD4 抗体 (AA 1-50) (ABIN7455159)

抗原

See all SMAD4 抗体
SMAD4 (SMAD Family Member 4 (SMAD4))

抗体类型

Recombinant Antibody

适用

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人, 小鼠

宿主

  • 80
  • 22
  • 1
  • 1

克隆类型

  • 63
  • 41
单克隆

标记

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This SMAD4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

BLR133J
  • 抗原表位

    • 13
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    • 1
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    AA 1-50

    原理

    Rabbit anti-SMAD4 Recombinant Monoclonal Antibody [BLR133J]

    免疫原

    between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 6 μL/1 mg lysate

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 01:01,00

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    SMAD4 (SMAD Family Member 4 (SMAD4))

    别名

    SMAD4

    背景

    Background: The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD4 forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. SMAD4 functions in the transforming growth factor-beta signaling pathway as well as the bone morphogenetic protein signaling pathway, regulating cell proliferation, angiogenesis, and increasing blood vessel hyperpermeability. [taken from NCBI Entrez Gene (Gene ID: 4089)].

    基因ID

    4089

    NCBI登录号

    NP_005350

    UniProt

    Q13485

    途径

    Cell Division Cycle, Chromatin Binding, Autophagy
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