Recombinant SMAD4 抗体 (AA 1-50)
Quick Overview for Recombinant SMAD4 抗体 (AA 1-50) (ABIN7455159)
抗原
See all SMAD4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-50
-
原理
- Rabbit anti-SMAD4 Recombinant Monoclonal Antibody [BLR133J]
-
免疫原
- between AA 1 and 50
-
亚型
- IgG
-
-
-
-
应用备注
-
IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 6 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- SMAD4 (SMAD Family Member 4 (SMAD4))
-
别名
- SMAD4
-
背景
- Background: The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD4 forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. SMAD4 functions in the transforming growth factor-beta signaling pathway as well as the bone morphogenetic protein signaling pathway, regulating cell proliferation, angiogenesis, and increasing blood vessel hyperpermeability. [taken from NCBI Entrez Gene (Gene ID: 4089)].
-
基因ID
- 4089
-
NCBI登录号
- NP_005350
-
UniProt
- Q13485
-
途径
- Cell Division Cycle, Chromatin Binding, Autophagy
抗原
-