Recombinant CEACAM1/5 抗体 (AA 35-433)
Quick Overview for Recombinant CEACAM1/5 抗体 (AA 35-433) (ABIN7455139)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 35-433
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原理
- Rabbit anti-CEACAM1/5 Recombinant Monoclonal Antibody [BLR032F]
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免疫原
- residues 35-433 (ECD)
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亚型
- IgG
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5) (N-Term) antibody
CEACAM1/5 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5) antibodyCEACAM1/5 适用: 人 FACS, WB, ELISA, cELISA, IHC (fro) 宿主: 小鼠 Monoclonal 4-3-17 unconjugated
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应用备注
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 20 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 17:40:00
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
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别名
- CEACAM1/5
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背景
- Background: Carcinoembryonic antigen related cell adhesion molecules 1 and 5 (CEACAM1 and CEACAM5) are members of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. CEACAM1 was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM5 is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, CEACAM5 may regulate differentiation, apoptosis, and cell polarity.
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基因ID
- 634, 1048
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NCBI登录号
- NP_001020083
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UniProt
- P13688, P06731
抗原
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