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CDK7 抗体 (C-Term)

This anti-CDK7 antibody is a 兔 多克隆 antibody detecting CDK7 in WB, IP, ICC 和 IHC (fp). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7455080
发货至: 中国

Quick Overview for CDK7 抗体 (C-Term) (ABIN7455080)

抗原

See all CDK7 抗体
CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

适用

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人, 小鼠, 大鼠

宿主

  • 82
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克隆类型

  • 75
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多克隆

标记

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This CDK7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 30
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    C-Term

    原理

    Rabbit anti-CDK7 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 300 and C-term

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    ICC: 1:100 - 1:500

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

    别名

    CDK7

    背景

    Background: Cyclin-dependent kinase 7 (CDK7) is a member of the CDK family of protein kinases that regulate cell cycle progression. CDK7 is the catalytic subunit in a trimeric complex with cyclin H and MAT1 that functions as a Cdk-activating kinase (CAK). CDK7 activates the kinase activities of CDK1, CDK2, CDK4, and CDK6 by threonine phosphorylation. In addition to its cell cycle function CDK7 has also been found to be an essential component of the transcription factor TFIIH. Several substrates of CDK7 are involved in transcription, further indicating a role in transcription.

    基因ID

    1022

    NCBI登录号

    NP_001790

    UniProt

    P50613

    途径

    Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
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