PHGDH 抗体 (AA 1-50)
Quick Overview for PHGDH 抗体 (AA 1-50) (ABIN7455052)
抗原
See all PHGDH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-PHGDH Antibody, Affinity Purified
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预测反应
- Bovine,Pig,Orangutan,Chimpanzee
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1 and 50
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亚型
- IgG
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应用备注
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IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
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别名
- PHGDH
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背景
- Background: D-3-phosphoglycerate dehydrogenase (PHGDH) is an enzyme involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptom [taken from NCBI Entrez Gene (Gene ID: 26227)].
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基因ID
- 26227
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NCBI登录号
- NP_006614
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UniProt
- O43175
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途径
- Metabolism of Steroid Hormones and Vitamin D, Warburg Effect
抗原
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