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PHGDH 抗体 (AA 1-50)

This 兔 多克隆 anti-PHGDH antibody specifically detects PHGDH in WB, IP 和 IHC (fp). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7455052
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PHGDH 抗体 (AA 1-50) (ABIN7455052)

抗原

See all PHGDH 抗体
PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

适用

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人, 小鼠

宿主

  • 56
  • 7
  • 1

克隆类型

  • 58
  • 6
多克隆

标记

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This PHGDH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 15
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    AA 1-50

    原理

    Rabbit anti-PHGDH Antibody, Affinity Purified

    预测反应

    Bovine,Pig,Orangutan,Chimpanzee

    纯化方法

    Affinity Purified

    免疫原

    Between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

    别名

    PHGDH

    背景

    Background: D-3-phosphoglycerate dehydrogenase (PHGDH) is an enzyme involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptom [taken from NCBI Entrez Gene (Gene ID: 26227)].

    基因ID

    26227

    NCBI登录号

    NP_006614

    UniProt

    O43175

    途径

    Metabolism of Steroid Hormones and Vitamin D, Warburg Effect
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