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PSME3 抗体 (AA 204-254)

This anti-PSME3 antibody is a 兔 多克隆 antibody detecting PSME3 in WB, IP 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7454979
发货至: 中国

Quick Overview for PSME3 抗体 (AA 204-254) (ABIN7454979)

抗原

See all PSME3 抗体
PSME3

适用

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  • 22
  • 16
  • 9
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  • 2
  • 2
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人, 小鼠

宿主

  • 42
  • 8

克隆类型

  • 44
  • 6
多克隆

标记

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  • 4
  • 4
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  • 1
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This PSME3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 204-254

    原理

    Rabbit anti-PSME3 Antibody, Affinity Purified

    预测反应

    Chicken,Pig,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    Between AA 204 and 254

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:500 - 1:2,500

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    PSME3

    别名

    PSME3

    背景

    Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME3 [proteasome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)] is the gamma subunit of the 11S regulator [taken from NCBI Entrez Gene (Gene ID: 10197)].

    基因ID

    10197

    NCBI登录号

    NP_005780

    UniProt

    P61289

    途径

    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
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