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- 抗原 See all PSME3 抗体
- PSME3
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSME3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- PSME3 Antibody detects endogenous levels of total PSME3.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PSME3, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PSME3 Primary Antibody
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anti-PSME3 (PSME3) (AA 7-254) antibody
PSME3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) antibodyKO Validated PSME3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (AA 2-252) antibodyPSME3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) antibodyPSME3 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (AA 1-254) antibodyPSME3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PSME3 (PSME3) (C-Term) antibodyPSME3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (N-Term) antibodyPSME3 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (AA 1-254) antibodyPSME3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (AA 48-97) antibodyPSME3 适用: 人, 大鼠, 小鼠, 犬, Pig, Cow, 豚鼠, 马, 兔, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (C-Term) antibodyPSME3 适用: 人, 大鼠, 小鼠, 犬, Pig, Cow, 豚鼠, 马, 兔, 斑马鱼, 小鸡, 非洲爪蟾, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PSME3
- 别名
- PSME3 (PSME3 产品)
- 别名
- AA410043 antibody, AU020960 antibody, Ki antibody, PA28gamma antibody, REGgamma antibody, pa28g antibody, Ab2-371 antibody, PA28-gamma antibody, PA28G antibody, REG-GAMMA antibody, psme3b antibody, proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) antibody, proteasome activator subunit 3 antibody, proteasome activator subunit 3 S homeolog antibody, Psme3 antibody, PSME3 antibody, psme3.S antibody
- 背景
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Description: Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (PubMed:25361978).
Gene: PSME3
- 分子量
- 30kDa
- 基因ID
- 10197
- UniProt
- P61289
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
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