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alpha Adducin 抗体 (AA 632-682)

This anti-alpha Adducin antibody is a 兔 多克隆 antibody detecting alpha Adducin in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7454952
发货至: 中国

Quick Overview for alpha Adducin 抗体 (AA 632-682) (ABIN7454952)

抗原

See all alpha Adducin (ADD1) 抗体
alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

适用

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宿主

  • 90
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克隆类型

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多克隆

标记

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This alpha Adducin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    AA 632-682

    原理

    Rabbit anti-Alpha-Adducin Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    Between AA 632 and 682

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:10,000 - 1:25,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

    别名

    Alpha-Adducin

    背景

    Background: Alpha-adducin is a member of the adducin family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C [taken from NCBI Entrez Gene (Gene ID: 118)].

    基因ID

    118

    NCBI登录号

    NP_001110

    UniProt

    P35611

    途径

    Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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