KIT 抗体 (AA 925-976)
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Quick Overview for KIT 抗体 (AA 925-976) (ABIN7454909)
抗原
See all KIT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 925-976
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原理
- Rabbit anti-c-Kit Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 925 and 976
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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别名
- c-Kit
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背景
- Background: c-Kit is the receptor for stem cell factor (mast cell growth factor). It is a transmembrane receptor with tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of the c-Kit receptor and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K) [taken from the Universal Protein Resource (UniProt) P10721].
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基因ID
- 3815
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NCBI登录号
- NP_000213
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UniProt
- P10721
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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