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SENP3 抗体 (AA 275-325)

SENP3 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7454900
发货至: 中国
  • 抗原 See all SENP3 抗体
    SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))
    抗原表位
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 275-325
    适用
    • 29
    • 15
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 29
    • 1
    克隆类型
    • 30
    多克隆
    标记
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SENP3 antibody is un-conjugated
    应用范围
    • 22
    • 13
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    原理
    Rabbit anti-SENP3 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 275 and 325
    亚型
    IgG
    Top Product
    Discover our top product SENP3 Primary Antibody
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))
    别名
    SENP3 (SENP3 产品)
    别名
    SMT3IP1 antibody, SSP3 antibody, Ulp1 antibody, AA408656 antibody, Smt3ip antibody, Smt3ip1 antibody, ssp3 antibody, smt3ip1 antibody, fa03d07 antibody, wu:fa03d07 antibody, senp3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3 antibody, SUMO/sentrin specific peptidase 3 antibody, Sumo1/sentrin/SMT3 specific peptidase 3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3b antibody, SUMO1/sentrin/SMT3 specific peptidase 3 L homeolog antibody, SENP3 antibody, Senp3 antibody, senp3 antibody, senp3b antibody, senp3.L antibody
    背景
    Background: Sentrin-specific protease 3 (SENP3) functions as a protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates.SENP3 deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability, and also deconjugates SUMO2 and SUMO3 from CDCA8. SENP3 can function as a redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. SENP3 is required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1 [taken from the Universal Protein Resource (UniProt) Q9H4L4].
    基因ID
    26168
    NCBI登录号
    NP_056485
    UniProt
    Q9H4L4
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