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SENP3 抗体

SENP3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7184127
发货至: 中国
  • 抗原 See all SENP3 抗体
    SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))
    适用
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    宿主
    • 29
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    克隆类型
    • 30
    多克隆
    标记
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    This SENP3 antibody is un-conjugated
    应用范围
    • 22
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from Internal of Human SENP3.
    亚型
    IgG
    Top Product
    Discover our top product SENP3 Primary Antibody
  • 应用备注
    WB:1:500-1:3000, IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))
    别名
    SENP3 (SENP3 产品)
    别名
    SMT3IP1 antibody, SSP3 antibody, Ulp1 antibody, AA408656 antibody, Smt3ip antibody, Smt3ip1 antibody, ssp3 antibody, smt3ip1 antibody, fa03d07 antibody, wu:fa03d07 antibody, senp3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3 antibody, SUMO/sentrin specific peptidase 3 antibody, Sumo1/sentrin/SMT3 specific peptidase 3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3b antibody, SUMO1/sentrin/SMT3 specific peptidase 3 L homeolog antibody, SENP3 antibody, Senp3 antibody, senp3 antibody, senp3b antibody, senp3.L antibody
    背景

    Background: Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

    Yeh E.T.H., Gene 248:1-14(2000).
    Choi S.J., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
    Wiemann S., Genome Res. 11:422-435(2001).

    Aliases: SENP3 antibody, SENP3_HUMAN antibody, Sentrin / SUMO specific protease 3 antibody, Sentrin specific protease 3 antibody, Sentrin-specific protease 3 antibody, Sentrin/SUMO-specific protease SENP3 antibody, SMT3IP1 antibody, SSP3 antibody, SUMO 1 specific protease 3 antibody, SUMO-1-specific protease 3 antibody, SUMO1 specific protease 3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3 antibody, SUSP3 antibody

    UniProt
    Q9H4L4
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