ZEB1 抗体 (AA 1074-1124)
Quick Overview for ZEB1 抗体 (AA 1074-1124) (ABIN7454797)
抗原
See all ZEB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1074-1124
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原理
- Rabbit anti-ZEB1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1074 and 1124
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亚型
- IgG
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anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (AA 967-1108) antibody
ZEB1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2A8A6 unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (AA 801-900) antibodyZEB1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (N-Term) antibodyZEB1 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (AA 1-260) antibodyZEB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) antibodyKO Validated ZEB1 适用: 人 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) antibodyZEB1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (Internal Region) antibodyZEB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (N-Term) antibodyZEB1 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (Internal Region) antibodyVerified ZEB1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (N-Term) antibodyZEB1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:200 - 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
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别名
- ZEB1
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背景
- Background: ZEB1 (zinc-finger E-box-binding homeobox 1), also known as TCF8 (transcription factor 8), is a delta-EF1/ZFH-1 C2H2-type zinc finger that bears seven C2H2-type zinc fingers and one homeobox DNA-binding domain. ZEB1 is a transcriptional repressor of interleukin-2 (IL-2). Mutations in the ZEB1 gene are associated with posterior corneal dystrophy type 3 (PPC3) a rare disorder characterized by metaplasia and overgrowth of corneal endothelial cells. ZEB1 appears to be critical to epithelial to mesenchymal transitions (EMT) during development and cancer metastasis. As a transcription factor involved in EMT, ZEB1 promotes EMT by repressing genes associated with the epithelial phenotype and activates genes associated with the mesenchymal phenotype.
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基因ID
- 6935
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NCBI登录号
- NP_110378
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UniProt
- P37275
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途径
- Regulation of Muscle Cell Differentiation
抗原
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