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ZEB1 抗体 (Internal Region)

ZEB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6266096
发货至: 中国
  • 抗原 See all ZEB1 抗体
    ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
    抗原表位
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 49
    • 20
    • 14
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 35
    • 13
    • 1
    克隆类型
    • 33
    • 16
    多克隆
    标记
    • 38
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZEB1 antibody is un-conjugated
    应用范围
    • 35
    • 14
    • 14
    • 12
    • 9
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    ZEB1 Antibody detects endogenous levels of total ZEB1.
    预测反应
    Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ZEB1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ZEB1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • Shao, Zhang, Ma, Lu, Meng, Li, Wang, Chen, Zhang, Han, Liu, Ma: "MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." in: Gene, Vol. 652, pp. 48-58, (2018) (PubMed).

    Li, Shen, Wang, Li, Wang, Jiang, Zhou, Feng: "EGCG regulates the cross-talk between JWA and topoisomerase IIα in non-small-cell lung cancer (NSCLC) cells." in: Scientific reports, Vol. 5, pp. 11009, (2016) (PubMed).

    Li, Zhang, Sun, Sun, Shi, Liu, Liu: "MicroRNA-181a regulates epithelial-mesenchymal transition by targeting PTEN in drug-resistant lung adenocarcinoma cells." in: International journal of oncology, Vol. 47, Issue 4, pp. 1379-92, (2016) (PubMed).

  • 抗原
    ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
    别名
    ZEB1 (ZEB1 产品)
    别名
    ZFH/[d]EF1 antibody, kheper antibody, zeb1 antibody, zfhx1 antibody, bzp antibody, zeb antibody, tcf8 antibody, areb6 antibody, nil2a antibody, zfhep antibody, nil-2a antibody, zfhx1a antibody, nil-2-a antibody, MGC97552 antibody, TCF8 antibody, AREB6 antibody, BZP antibody, DELTAEF1 antibody, FECD6 antibody, NIL2A antibody, PPCD3 antibody, ZFHEP antibody, ZFHX1A antibody, 3110032K11Rik antibody, MEB1 antibody, Nil2 antibody, TCF-8 antibody, Tcf18 antibody, Tcf8 antibody, Tw antibody, ZEB antibody, Zfhep antibody, Zfhx1a antibody, Zfx1a antibody, Zfx1ha antibody, [delta]EF1 antibody, deltaEF1 antibody, deltaef1 antibody, fecd6 antibody, zinc finger E-box binding homeobox 1b antibody, zinc finger E-box binding homeobox 1 antibody, zinc finger E-box binding homeobox 1 S homeolog antibody, zeb1b antibody, zeb1 antibody, ZEB1 antibody, Zeb1 antibody, zeb1.S antibody
    背景

    Description: Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.

    Gene: ZEB1

    分子量
    124kDa
    基因ID
    6935
    UniProt
    P37275
    途径
    Regulation of Muscle Cell Differentiation
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