XPA 抗体 (AA 1-50)
Quick Overview for XPA 抗体 (AA 1-50) (ABIN7454782)
抗原
See all XPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-XPA Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1 and 50
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亚型
- IgG
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应用备注
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IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
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别名
- XPA
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背景
- Background: Mutations in XPA (xeroderma pigmentosum group A-complementing protein) are the cause of xeroderma pigmentosum A (XP-A), an autosomal recessive disease that is mainly characterized by a susceptibility to UV-induced skin cancer and in some cases neurological abnormalities. XPA is one of seven XP complementation groups that have been identified. The XP complementation groups represent genes critical to the nucleotide excision repair (NER) pathway. XPA is thought to function in the recognition of DNA damage and as a processivity factor for XPF and XPG.
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基因ID
- 7507
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NCBI登录号
- NP_000371
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UniProt
- P23025
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途径
- DNA Damage Repair
抗原
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