电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PML 抗体 (AA 575-625)

The 兔 多克隆 anti-PML antibody (ABIN7454723) specifically detects PML in WB, IP 和 IHC (fp). The antibody is reactive with 人 samples.
产品编号 ABIN7454723
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PML 抗体 (AA 575-625) (ABIN7454723)

抗原

See all PML 抗体
PML (Promyelocytic Leukemia (PML))

适用

  • 96
  • 58
  • 43
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 112
  • 11

克隆类型

  • 102
  • 21
多克隆

标记

  • 56
  • 9
  • 7
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PML antibody is un-conjugated

应用范围

  • 79
  • 52
  • 46
  • 29
  • 27
  • 20
  • 19
  • 13
  • 12
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 28
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 575-625

    原理

    Rabbit anti-PML Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 575 and 625

    亚型

    IgG
  • 应用备注

    IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    PML (Promyelocytic Leukemia (PML))

    别名

    PML

    背景

    Background: PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia.

    基因ID

    5371

    NCBI登录号

    NP_150241

    UniProt

    P29590

    途径

    p53 Pathway, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
You are here: