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VCP 抗体 (AA 1-50)

This anti-VCP antibody is a 兔 多克隆 antibody detecting VCP in WB, IP 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7454649
发货至: 中国

Quick Overview for VCP 抗体 (AA 1-50) (ABIN7454649)

抗原

See all VCP 抗体
VCP (Valosin Containing Protein (VCP))

适用

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人, 小鼠

宿主

  • 83
  • 20
  • 2

克隆类型

  • 74
  • 31
多克隆

标记

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This VCP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 12
    • 11
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    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
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    • 1
    • 1
    AA 1-50

    原理

    Rabbit anti-VCP Antibody, Affinity Purified

    预测反应

    Rat,Zebrafish,Bovine,Pig

    纯化方法

    Affinity Purified

    免疫原

    between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 1 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    VCP (Valosin Containing Protein (VCP))

    别名

    VCP

    背景

    Background: Valosin-containing protein (VCP) is a multifunctional protein that is proposed to be involved in vesicle transport and fusion for protein trafficking, 26S proteasome function in ubiquitin-based degradation pathways, and the assembly of peroxisomes. Mutations in the human VCP gene have been associated with diseases such as inclusion body myopathy, Paget disease of the bone, and frontotemporal dementia (IBMPFD). VCP can inhibit apoptosis and may play a role in tumorigenesis.

    基因ID

    7415

    NCBI登录号

    NP_009057

    UniProt

    P55072

    途径

    ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway
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