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NONO 抗体 (AA 350-400)

This anti-NONO antibody is a 兔 多克隆 antibody detecting NONO in WB, IP 和 IHC (fp). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7454648
发货至: 中国

Quick Overview for NONO 抗体 (AA 350-400) (ABIN7454648)

抗原

See all NONO 抗体
NONO (Non-POU Domain Containing, Octamer-Binding (NONO))

适用

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  • 37
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  • 1
人, 小鼠, 大鼠

宿主

  • 70
  • 6
  • 2

克隆类型

  • 61
  • 17
多克隆

标记

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  • 5
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  • 2
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  • 1
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  • 1
  • 1
  • 1
  • 1
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This NONO antibody is un-conjugated

应用范围

  • 60
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  • 14
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  • 10
  • 5
  • 3
  • 1
  • 1
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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 15
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 350-400

    原理

    Rabbit anti-NONO Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 350 and 400

    亚型

    IgG
  • 应用备注

    IHC: 1:200 - 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    NONO (Non-POU Domain Containing, Octamer-Binding (NONO))

    别名

    NONO

    背景

    Background: Non-POU-domain-containing octamer binding protein (NONO) is a member of the DBHS (drosophila behavior, human splicing) domain-containing family and is an RNA- and DNA- binding protein. NONO and other DBHS domain-containing proteins are multifunctional and are reported to be involved in transcriptional regulation, mRNA processing, and DNA non-homologous end joining (NHEJ). NONO functions as a coregulator of the androgen receptor (AR) and also regulates cAMP transcriptional activity by interacting with gene promoter elements. NONO is also involved in pre-mRNA splicing through an interaction with U5 snRNA and can stimulate DNA nonhomologous end joining (NHEJ) through the interaction with ku70/G22p and ku80/XRCC5 dimers.

    基因ID

    4841

    NCBI登录号

    NP_031389

    UniProt

    Q15233
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