FOXO3 抗体 (AA 250-300)
Quick Overview for FOXO3 抗体 (AA 250-300) (ABIN7454631)
抗原
See all FOXO3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-300
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原理
- Rabbit anti-FOXO3a Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 250 and 300
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亚型
- IgG
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应用备注
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IHC: 1:200 - 1:1,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:1,000 - 1:5,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FOXO3 (Forkhead Box O3 (FOXO3))
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别名
- FOXO3a
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背景
- Background: Forkhead box protein 03A (FOXO3a) belongs to a large family of Forkhead proteins that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). FOXO3a is a transcription factor that functions to induce apoptosis in the absence of survival factors and in response to oxidative stress. Under conditions of oxidative stress FOXO3a is acetylated and localized to the nucleus where it may act as a transcriptional repressor.
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基因ID
- 2309
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NCBI登录号
- NP_963853
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UniProt
- O43524
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
抗原
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