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FOXO3 抗体 (AA 250-300)

This anti-FOXO3 antibody is a 兔 多克隆 antibody detecting FOXO3 in WB, IP 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7454631
发货至: 中国

Quick Overview for FOXO3 抗体 (AA 250-300) (ABIN7454631)

抗原

See all FOXO3 抗体
FOXO3 (Forkhead Box O3 (FOXO3))

适用

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人, 小鼠

宿主

  • 125
  • 6
  • 1
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克隆类型

  • 110
  • 23
多克隆

标记

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This FOXO3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 38
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    AA 250-300

    原理

    Rabbit anti-FOXO3a Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 250 and 300

    亚型

    IgG
  • 应用备注

    IHC: 1:200 - 1:1,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:1,000 - 1:5,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    FOXO3 (Forkhead Box O3 (FOXO3))

    别名

    FOXO3a

    背景

    Background: Forkhead box protein 03A (FOXO3a) belongs to a large family of Forkhead proteins that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). FOXO3a is a transcription factor that functions to induce apoptosis in the absence of survival factors and in response to oxidative stress. Under conditions of oxidative stress FOXO3a is acetylated and localized to the nucleus where it may act as a transcriptional repressor.

    基因ID

    2309

    NCBI登录号

    NP_963853

    UniProt

    O43524

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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