CHMP2B 抗体 (AA 163-213)
Quick Overview for CHMP2B 抗体 (AA 163-213) (ABIN7454583)
抗原
See all CHMP2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 163-213
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原理
- Rabbit anti-CHMP2B Antibody, Affinity Purified
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预测反应
- X. laevis,X. tropicalis,Chicken,Bovine,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- Between AA 163 and 213
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亚型
- IgG
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anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 1-213) antibody
CHMP2B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 1-213) antibodyCHMP2B 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 1-213) antibodyCHMP2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) antibodyCHMP2B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 31-120) antibodyCHMP2B 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 1-213) antibodyCHMP2B 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2H6-1E6 unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 1-30), (N-Term) antibodyCHMP2B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33284 unconjugated
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: Not recommended
WB: 1:1,000 - 1:5,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
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别名
- CHMP2B
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背景
- Background: Charged multivesicular body protein 2b (CHMP2B) is a probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4 [taken from the Universal Protein Resource (UniProt) Q9UQN3].
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基因ID
- 25978
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NCBI登录号
- NP_054762
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UniProt
- Q9UQN3
抗原
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