Desmoplakin 抗体 (AA 1900-1950)
Quick Overview for Desmoplakin 抗体 (AA 1900-1950) (ABIN7454486)
抗原
See all Desmoplakin (DSP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1900-1950
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原理
- Rabbit anti-Desmoplakin Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1900 and 1950
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亚型
- IgG
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anti-Desmoplakin (DSP) (AA 2609-2822) antibody
DSP 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) antibodyDSP 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) antibodyDSP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) (AA 1-100) antibodyDSP 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) antibodyDSP 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) (C-Term) antibodyDSP 适用: 人, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Desmoplakin (DSP) (Internal Region) antibodyVerified DSP 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Desmoplakin (DSP) (AA 2750-2850) antibodyDSP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Desmoplakin (DSP)
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别名
- Desmoplakin
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背景
- Background: Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in DSP, the gene encoding desmoplakin, are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus [taken from NCBI Entrez Gene (Gene ID: 1832)].
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基因ID
- 1832
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NCBI登录号
- NP_004406
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UniProt
- P15924
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途径
- Cell-Cell Junction Organization
抗原
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