BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 175-225) 抗体
Quick Overview for BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 175-225) 抗体 (ABIN7454455)
抗原
See all BRISC and BRCA1 A Complex Member 1 (BABAM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 175-225
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原理
- Rabbit anti-MERIT40 Antibody, Affinity Purified
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预测反应
- Mouse,Rat,Bovine,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 175 and 225
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亚型
- IgG
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anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 36-85) antibody
BABAM1 适用: 人, 小鼠, 犬, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 1-329) antibodyBABAM1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 116-143) antibodyBABAM1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20468 unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 9-37), (N-Term) antibodyBABAM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB20467 unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (N-Term) antibodyBABAM1 适用: 人, 小鼠, 犬, 豚鼠, 马, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-BRISC and BRCA1 A Complex Member 1 (BABAM1) (Middle Region) antibodyBABAM1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- BRISC and BRCA1 A Complex Member 1 (BABAM1)
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别名
- MERIT40
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背景
- Background: MERIT40 (mediator of RAP80 interactions and targeting subunit of 40 kDa) is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites and leads to targeting of the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. MERIT40 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin [taken from the Universal Protein Resource (UniProt) Q9NWV8].
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基因ID
- 29086
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NCBI登录号
- NP_054892
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UniProt
- Q9NWV8
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
-
