ZEB2 抗体 (AA 750-800)
Quick Overview for ZEB2 抗体 (AA 750-800) (ABIN7454452)
抗原
See all ZEB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 750-800
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原理
- Rabbit anti-ZEB2/SIP Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 750 and 800
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-ZEB2/SIP antibody A302-474A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))
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别名
- ZEB2/SIP
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背景
- Background: Smad interacting protein 1 (SIP1) is a transcriptional inhibitor that binds to the DNA sequence, 5'-CACCT-3', in different promoters. SIP1 has been shown to repress the transcription of E-cadherin. Defects in the gene which encodes for SIP1, ZEB2, are the cause of Hirschsprung disease-mental retardation syndrome (Hirschsprung disease) also known as Mowat-Wilson syndrome (MWS). Hirschsprung disease is a rare autosomal dominant complex developmental disorder [taken from the Universal Protein Resource (UniProt) O60315].
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基因ID
- 9839
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NCBI登录号
- NP_055610
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UniProt
- O60315
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途径
- Tube Formation
抗原
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