RANGAP1 抗体 (AA 400-450)
Quick Overview for RANGAP1 抗体 (AA 400-450) (ABIN7454428)
抗原
See all RANGAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-450
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原理
- Rabbit anti-RanGAP1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 400 and 450
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-RanGAP1 antibody A302-026A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
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别名
- RanGAP1
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背景
- Background: The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Ran-specific GTPase-activating protein 1 (RanGAP1) induces the GTPase activity of the RAN small GTPase. The Ran GTPase plays a role in spatial information and nucleocytoplasmic transport. RanGAP1 is the antagonist of the GEF RCC1 which keeps RAN in the active GTP-bound state.
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基因ID
- 5905
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NCBI登录号
- NP_002874
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UniProt
- P46060
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途径
- M Phase, Protein targeting to Nucleus
抗原
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