RANGAP1 抗体 (AA 400-450)
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- 抗原 See all RANGAP1 抗体
- RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
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抗原表位
- AA 400-450
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RANGAP1 antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-RanGAP1 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 400 and 450
- 亚型
- IgG
- Top Product
- Discover our top product RANGAP1 Primary Antibody
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- 应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-RanGAP1 antibody A302-026A.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
- 别名
- RanGAP1 (RANGAP1 产品)
- 背景
- Background: The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Ran-specific GTPase-activating protein 1 (RanGAP1) induces the GTPase activity of the RAN small GTPase. The Ran GTPase plays a role in spatial information and nucleocytoplasmic transport. RanGAP1 is the antagonist of the GEF RCC1 which keeps RAN in the active GTP-bound state.
- 基因ID
- 5905
- NCBI登录号
- NP_002874
- UniProt
- P46060
- 途径
- M Phase, Protein targeting to Nucleus
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