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RANGAP1 抗体 (AA 400-450)

The 兔 多克隆 anti-RANGAP1 antibody is suitable to detect RANGAP1 in samples from 人. It has been validated for IP 和 IHC (fp).
产品编号 ABIN7454428
发货至: 中国
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Room 801-803
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Quick Overview for RANGAP1 抗体 (AA 400-450) (ABIN7454428)

抗原

See all RANGAP1 抗体
RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This RANGAP1 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    AA 400-450

    原理

    Rabbit anti-RanGAP1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 400 and 450

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. Use rabbit anti-RanGAP1 antibody A302-026A.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

    别名

    RanGAP1

    背景

    Background: The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Ran-specific GTPase-activating protein 1 (RanGAP1) induces the GTPase activity of the RAN small GTPase. The Ran GTPase plays a role in spatial information and nucleocytoplasmic transport. RanGAP1 is the antagonist of the GEF RCC1 which keeps RAN in the active GTP-bound state.

    基因ID

    5905

    NCBI登录号

    NP_002874

    UniProt

    P46060

    途径

    M Phase, Protein targeting to Nucleus
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