PDZ-RhoGEF (AA 125-175) 抗体
This 兔 多克隆 antibody specifically detects PDZ-RhoGEF in IHC (fp) 和 IP. It exhibits reactivity toward 人.
产品编号 ABIN7454424
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for PDZ-RhoGEF (AA 125-175) 抗体 (ABIN7454424)
抗原
PDZ-RhoGEF
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)
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抗原表位
- AA 125-175
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原理
- Rabbit anti-PDZ-RhoGEF Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 125 and 175
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亚型
- IgG
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anti-PDZ-RhoGEF (N-Term) antibody
适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-PDZ-RhoGEF antibody A301-952A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PDZ-RhoGEF
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背景
- Background: PDZ-RhoGEF. (PDZ domain-containing Rho guanine nucleotide exchange factor) catalyzes the exchange of GDP for GTP on the GTPase, Rho, to activate downstream signaling pathways. It contains a PDZ [post synaptic density protein (PSD95), Drosophila dis large tumor suppressor (DIgA), and zonula occludens-1 protein (zo-1)] domain which is an 80-90 amino acid structural domain found in signaling proteins in bacteria, yeast, plants, and animals. PDZ-RhoGEF has been shown to be important to cell migration and the regulation of adhesion movement and trailing edge retraction.
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基因ID
- 9826
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NCBI登录号
- NP_055599
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UniProt
- O15085
抗原
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