PDZ-RhoGEF (AA 1472-1522) 抗体
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Quick Overview for PDZ-RhoGEF (AA 1472-1522) 抗体 (ABIN7448721)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1472-1522
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原理
- Rabbit anti-PDZ-RhoGEF IHC Antibody, Affinity Purified
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预测反应
- Gorilla,Chimpanzee
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1472 and 1522
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亚型
- IgG
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应用备注
- 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 100 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PDZ-RhoGEF
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背景
- Background: PDZ-RhoGEF. (PDZ domain-containing Rho guanine nucleotide exchange factor) catalyzes the exchange of GDP for GTP on the GTPase, Rho, to activate downstream signaling pathways. It contains a PDZ [post synaptic density protein (PSD95), Drosophila dis large tumor suppressor (DIgA), and zonula occludens-1 protein (zo-1)] domain which is an 80-90 amino acid structural domain found in signaling proteins in bacteria, yeast, plants, and animals. PDZ-RhoGEF has been shown to be important to cell migration and the regulation of adhesion movement and trailing edge retraction.
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基因ID
- 9826
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NCBI登录号
- NP_055599
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UniProt
- O15085
抗原
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