GRB10 抗体 (AA 100-150)
Quick Overview for GRB10 抗体 (AA 100-150) (ABIN7454420)
抗原
See all GRB10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-150
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原理
- Rabbit anti-GRB10 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 100 and 150
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亚型
- IgG
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anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 392-594) antibody
GRB10 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 61-150) antibodyGRB10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (Ser428) antibodyGRB10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 1-100) antibodyGRB10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (N-Term) antibodyGRB10 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 33-82) antibodyGRB10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 1-536) antibodyGRB10 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 61-150) antibodyGRB10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (Internal Region) antibodyVerified GRB10 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (pTyr67) antibodyGRB10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-GRB10 antibody A301-734A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))
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别名
- GRB10
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背景
- Background: Growth factor receptor-bound protein 10 (GRB10) is a member of a family of adaptor proteins that bind to a variety of growth factor receptors to regulate receptor signaling and mediate signals for a variety of processes such as metabolism, growth, apoptosis, and migration. As a dimer, via its BPS (between PH and SH2) and SH2 (src-homology 2) domains, GRB10 associates with the insulin receptor (IR) as well as the insulin-like growth factor receptor (IGFR). GRB10's association with the IR has been shown to have inhibitory effects on insulin-induced kinase signaling, however studies have also reported that GRB10 can also have positive effects on IR signaling. It is suggested that GRB10 can serve in cellular functions independent of an interaction with the IR.
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基因ID
- 2887
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NCBI登录号
- NP_005302
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UniProt
- Q13322
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途径
- Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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