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OSR1 抗体 (AA 325-375)

This anti-OSR1 antibody is a 兔 多克隆 antibody detecting OSR1 in IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7454414
发货至: 中国

Quick Overview for OSR1 抗体 (AA 325-375) (ABIN7454414)

抗原

See all OSR1 抗体
OSR1 (Odd-Skipped Related 1 (OSR1))

适用

  • 40
  • 8
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 35
  • 5

克隆类型

  • 35
  • 5
多克隆

标记

  • 23
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This OSR1 antibody is un-conjugated

应用范围

  • 23
  • 12
  • 10
  • 7
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 10
    • 9
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 325-375

    原理

    Rabbit anti-OSR1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 325 and 375

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. Use rabbit anti-OSR1 antibody A301-579A.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    OSR1 (Odd-Skipped Related 1 (OSR1))

    别名

    OSR1

    背景

    Background: Oxidative stress responsive 1 (OSR1) is a STE20-related kinase involved in ion transport and fluid and ion homeostasis. OSR1 interacts with SPAK (STE20/SPS1-reated proline/alanine-rich kinase) and together are activated by the upstream kinase WNK1 [with no K (lysine) protein kinase-1]. Activation of OSR1 and SPAK by WNK1 results in the phosphorylation and activation of NKCC1 (Na+-K+-2Cl- co-transporter 1) for the control of cell volume and blood pressure.

    基因ID

    9943

    NCBI登录号

    NP_005100

    UniProt

    O95747

    途径

    Tube Formation
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