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LIG1 抗体 (AA 200-250)

This anti-LIG1 antibody is a 兔 多克隆 antibody detecting LIG1 in IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7454389
发货至: 中国

Quick Overview for LIG1 抗体 (AA 200-250) (ABIN7454389)

抗原

See all LIG1 抗体
LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))

适用

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宿主

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克隆类型

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多克隆

标记

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This LIG1 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    AA 200-250

    原理

    Rabbit anti-DNA Ligase 1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 200 and 250

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))

    别名

    DNA Ligase 1

    背景

    Background: DNA ligase 1 catalyzes the joining of double-stranded DNA ends during replication, recombination, and repair. Structurally, DNA ligase 1 is toroidal and encircles nicked DNA substrates. The 9-1-1 complex, a DNA damage checkpoint complex, has been reported to associate with DNA ligase 1 and stimulate ligase activity. Mutations in DNA ligase 1 result in immunodeficiency and increased sensitivity to DNA-damaging agents.

    基因ID

    3978

    NCBI登录号

    NP_000225

    UniProt

    P18858

    途径

    Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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