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KDM4A 抗体 (AA 350-400)

This 兔 多克隆 anti-KDM4A antibody specifically detects KDM4A in IP 和 IHC (fp). The antibody is reactive with 人 samples.
产品编号 ABIN7454377
发货至: 中国
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Quick Overview for KDM4A 抗体 (AA 350-400) (ABIN7454377)

抗原

See all KDM4A 抗体
KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

适用

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宿主

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克隆类型

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多克隆

标记

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This KDM4A antibody is un-conjugated

应用范围

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Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
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    AA 350-400

    原理

    Rabbit anti-JMJD2A Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 350 and 400

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. Use rabbit anti-JMJD2A antibody A300-861A.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

    别名

    JMJD2A

    背景

    Background: JMJD2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2A is a trimethylation-specific demethylase and functions as a transcriptional repressor. JMJD2A interacts with pRb and class one histone deacetylases to mediate repression of E2F-regulated promoters.

    基因ID

    9682

    NCBI登录号

    NP_055478

    UniProt

    O75164

    途径

    Warburg Effect
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