KDM4A 抗体 (AA 350-400)
Quick Overview for KDM4A 抗体 (AA 350-400) (ABIN7454377)
抗原
See all KDM4A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-400
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原理
- Rabbit anti-JMJD2A Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 350 and 400
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-JMJD2A antibody A300-861A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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别名
- JMJD2A
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背景
- Background: JMJD2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2A is a trimethylation-specific demethylase and functions as a transcriptional repressor. JMJD2A interacts with pRb and class one histone deacetylases to mediate repression of E2F-regulated promoters.
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基因ID
- 9682
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NCBI登录号
- NP_055478
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UniProt
- O75164
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途径
- Warburg Effect
抗原
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