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APOA1 抗体 (FITC)

This anti-APOA1 antibody is a 山羊 多克隆 antibody detecting APOA1 in . Suitable for 人.
产品编号 ABIN7454055
发货至: 中国

Quick Overview for APOA1 抗体 (FITC) (ABIN7454055)

抗原

See all APOA1 抗体
APOA1 (Apolipoprotein A-I (APOA1))

适用

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宿主

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山羊

克隆类型

  • 124
  • 67
多克隆

标记

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This APOA1 antibody is conjugated to FITC

应用范围

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克隆位点

F03
  • 原理

    Goat anti-Human Apo AI [F03] Antibody FITC Conjugated

    免疫原

    Human Apolipoprotein AI

    亚型

    IgG
  • 限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, pH 7.2

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    APOA1 (Apolipoprotein A-I (APOA1))

    别名

    ApoAI

    背景

    Background: Apo AI comprises approximately 70 % of the protein moiety in HDL. It is a single polypeptide chain consisting of 243 amino acid residues without disulfide bound and with glutamic acid as the C-terminal residue and aspartic acid as the N-terminal residue. The molecular weight is reported to be 28 kDa (Brewer et al., 1978). The roles of Apo AI in HDL function include reverse cholesterol transportation, lipid cholesterol binding, lecithin-cholesterol acyl transferase (LCAT) activation, and receptor binding, which is responsible for cholesterol esterification in plasma. Besides participate in cholesterol metabolism, Apo AI and HDL also suppress neutrophil activation, inhibit bacterial endotoxin, induce trypanosomal lysis, and other physiological activities. (Brouillette et al., 2001). Apo AI levels may be inversely related to the risk of coronary disease. In previous research, Apo AI may affect diet-induced inflammation by either directly or indirectly altering lipid rafts. (Cheng et al., 2012)

    基因ID

    335

    NCBI登录号

    NP_000030

    UniProt

    P02647

    途径

    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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