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Recombinant PD-L1 抗体 (C-Term)

The 兔 单克隆 anti-PD-L1 antibody (Clone BLR020E) (ABIN7454042) specifically detects PD-L1 in WB, FACS, IHC, IP, IF (p), IF/ICC 和 mIF. The antibody is reactive with 人 samples.
产品编号 ABIN7454042
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant PD-L1 抗体 (C-Term) (ABIN7454042)

抗原

See all PD-L1 抗体
PD-L1 (CD274 (PD-L1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This PD-L1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (fixed cells) (IF/ICC), Multiplex Immunofluorescence (mIF)

克隆位点

BLR020E
  • 抗原表位

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    C-Term

    原理

    Rabbit anti-PD-L1 Recombinant Monoclonal Antibody [BLR020E] - BSA-Free

    纯化方法

    Purified

    免疫原

    between AA 250 to 290 (C-term)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1000 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2 - 8 °C

    有效期

    12 months
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    PD-L1

    背景

    PD-L1 is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. PD-L1 is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma [taken from NCBI Entrez Gene (Gene ID: 55193)].

    基因ID

    29126

    UniProt

    Q9NZQ7

    途径

    Cancer Immune Checkpoints
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