Recombinant Cadherin 5 抗体 (AA 25-595)
Quick Overview for Recombinant Cadherin 5 抗体 (AA 25-595) (ABIN7453992)
抗原
See all Cadherin 5 (CDH5) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 25-595
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原理
- Rabbit anti-VE-Cadherin Recombinant Monoclonal Antibody [BLR239K]
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免疫原
- residues 25-595 (ECD)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Cadherin 5 (CDH5)
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别名
- VE-Cadherin
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背景
- Background: Cadherins are calcium-dependent cell adhesion proteins that preferentially interact with themselves in a homophilic manner in adjacent cells. VE-Cadherin, or Cadherin-5 plays an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton and acts in concert with KRIT1 and MPP5 to establish and maintain correct endothelial cell polarity and vascular lumen. [taken from the Universal Protein Resource (UniProt) P33151].
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基因ID
- 12562
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NCBI登录号
- NP_033998
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UniProt
- P55284
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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