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储存条件
4 °C
有效期
12 months
抗原
CD11b (ITGAM)
(Integrin alpha M (ITGAM))
别名
CD11b
背景
Background: CD11b is the most commonly used name for Integrin alpha M (ITGAM). Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAM combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). ITGAM/ITGB2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. [taken from NCBI Entrez Gene (Gene ID: 3684)].