BAF53A 抗体 (AA 25-75)
Quick Overview for BAF53A 抗体 (AA 25-75) (ABIN7453898)
抗原
See all BAF53A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-75
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原理
- Rabbit anti-BAF53A Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 25 and 75
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亚型
- IgG
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应用备注
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- BAF53A (Actin-Like 6A (BAF53A))
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别名
- BAF53A
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背景
- Background: BAF53A is a 53kd subunit of the BAF (BRG1/brm-associated factor) complex, a SWI/SNF chromatin remodeling and histone acetyltransferase complex that functions in the regulation of gene transcription. In the BAF complex, BAF53A is important to the ATPase activity of SMARCA4/BRG1 and the association of the BAF complex with chromatin. BAF53A also appears to be important to the formation of higher-order chromatin structure and has been shown to associate with mitotic chromosomes. Recently, BAF53A has been found to interact with p53 and repress p53-mediated gene transcription in a BRG1-independent manner.
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基因ID
- 86
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NCBI登录号
- NP_004292
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UniProt
- O96019
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途径
- Chromatin Binding, Photoperiodism
抗原
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