ERCC5 抗体 (AA 650-700)
Quick Overview for ERCC5 抗体 (AA 650-700) (ABIN7453883)
抗原
See all ERCC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 650-700
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原理
- Rabbit anti-ERCC5/XPG Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 650 and 700
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亚型
- IgG
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应用备注
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
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别名
- ERCC5/XPG
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背景
- Background: ERCC5 is a single-stranded DNA endonuclease involved in DNA excision repair. ERCC5 is an important component of the nucleotide excision repair (NER) pathway which is critical to the repair of DNA lesions caused by exposure to UV light. Defects in ERCC5 are the cause of xeroderma pigmentosum, an autosomal recessive disease characterized by a hypersensitivity to sunlight and a high predisposition to cancer on UV-exposed areas.
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基因ID
- 2073
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NCBI登录号
- NP_000114
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UniProt
- P28715
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途径
- DNA Damage Repair
抗原
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