STK39 抗体 (AA 375-425)
Quick Overview for STK39 抗体 (AA 375-425) (ABIN7453840)
抗原
See all STK39 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 375-425
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原理
- Rabbit anti-SPAK Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 375 and 425
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- STK39 (serine threonine Kinase 39 (STK39))
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别名
- SPAK
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背景
- Background: STE20/SPS1-related proline-alanine rich protein kinase (SPAK) is a serine/threonine kinase that is thought to function in the cellular stress response pathway. This kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. Catalytically active SPAK specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress [taken from NCBI Entrez Gene (GeneID: 27347)].
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基因ID
- 27347
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UniProt
- Q9UEW8
抗原
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