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Prohibitin 抗体 (AA 222-272)

The 兔 多克隆 anti-Prohibitin antibody is suitable to detect Prohibitin in samples from 人. It has been validated for WB, IHC (fp) 和 IP.
产品编号 ABIN7453838
发货至: 中国
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Room 801-803
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Quick Overview for Prohibitin 抗体 (AA 222-272) (ABIN7453838)

抗原

See all Prohibitin (PHB) 抗体
Prohibitin (PHB)

适用

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宿主

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克隆类型

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多克隆

标记

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This Prohibitin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)
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    AA 222-272

    原理

    Rabbit anti-Prohibitin Antibody, Affinity Purified

    预测反应

    Mouse,Rat,Bovine

    纯化方法

    Affinity Purified

    免疫原

    between AA 222 and 272

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: Not recommended

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Prohibitin (PHB)

    别名

    Prohibitin

    背景

    Background: Prohibitin (PHB) has been identified as a tumor suppressor protein that can repress E2F-mediated transcription and arrest cell cycle progression. It has recently been shown to associate with members of the minichromosome maintenance complex such as MCM2, MCM5, and MCM7 and therefore is thought to impart its growth inhibitory effects via association with the replication machinery. Prohibitin is also implicated in regulating mitochondrial respiration and playing a role in aging.

    基因ID

    5245

    NCBI登录号

    NP_002625

    UniProt

    P35232

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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