UVRAG 抗体 (AA 649-699)
Quick Overview for UVRAG 抗体 (AA 649-699) (ABIN7453808)
抗原
See all UVRAG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 649-699
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原理
- Rabbit anti-UVRAG Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 649 and 699
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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别名
- UVRAG
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背景
- Background: UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells.
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基因ID
- 7405
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NCBI登录号
- NP_003360
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UniProt
- Q9P2Y5
抗原
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