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UVRAG 抗体 (AA 649-699)

This anti-UVRAG antibody is a 兔 多克隆 antibody detecting UVRAG in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453808
发货至: 中国

Quick Overview for UVRAG 抗体 (AA 649-699) (ABIN7453808)

抗原

See all UVRAG 抗体
UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

适用

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宿主

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克隆类型

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多克隆

标记

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This UVRAG antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
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    AA 649-699

    原理

    Rabbit anti-UVRAG Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 649 and 699

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

    别名

    UVRAG

    背景

    Background: UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells.

    基因ID

    7405

    NCBI登录号

    NP_003360

    UniProt

    Q9P2Y5
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