UBA2 抗体 (AA 525-575)
Quick Overview for UBA2 抗体 (AA 525-575) (ABIN7453775)
抗原
See all UBA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 525-575
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原理
- Rabbit anti-SAE2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 525 and 575
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
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别名
- SAE2
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背景
- Background: SAE2 (SUMO-activating enzyme subunit 2) is also known as UBA2 (ubiquitin-like modifier activating enzyme 2). Heterodimers of SAE1 and SAE2 act as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. Heterodimers mediate ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2 [taken from the Universal Protein Resource (UniProt) Q9UBT2].
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基因ID
- 10054
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NCBI登录号
- NP_005490
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UniProt
- Q9UBT2
抗原
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