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UBA2 抗体 (AA 525-575)

The 兔 多克隆 anti-UBA2 antibody is suitable to detect UBA2 in samples from 人 和 小鼠. It has been validated for WB, IP 和 IHC (fp).
产品编号 ABIN7453775
发货至: 中国
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Quick Overview for UBA2 抗体 (AA 525-575) (ABIN7453775)

抗原

See all UBA2 抗体
UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

适用

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  • 1
人, 小鼠

宿主

  • 54
  • 7
  • 1

克隆类型

  • 37
  • 25
多克隆

标记

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  • 1
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This UBA2 antibody is un-conjugated

应用范围

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  • 31
  • 25
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  • 7
  • 3
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  • 1
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  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 525-575

    原理

    Rabbit anti-SAE2 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 525 and 575

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

    别名

    SAE2

    背景

    Background: SAE2 (SUMO-activating enzyme subunit 2) is also known as UBA2 (ubiquitin-like modifier activating enzyme 2). Heterodimers of SAE1 and SAE2 act as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. Heterodimers mediate ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2 [taken from the Universal Protein Resource (UniProt) Q9UBT2].

    基因ID

    10054

    NCBI登录号

    NP_005490

    UniProt

    Q9UBT2
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