OSR1 抗体 (AA 375-425)
Quick Overview for OSR1 抗体 (AA 375-425) (ABIN7453750)
抗原
See all OSR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 375-425
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原理
- Rabbit anti-OSR1 Antibody, Affinity Purified
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预测反应
- Mouse,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 375 and 425
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- OSR1 (Odd-Skipped Related 1 (OSR1))
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别名
- OSR1
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背景
- Background: Oxidative stress responsive 1 (OSR1) is a STE20-related kinase involved in ion transport and fluid and ion homeostasis. OSR1 interacts with SPAK (STE20/SPS1-reated proline/alanine-rich kinase) and together are activated by the upstream kinase WNK1 [with no K (lysine) protein kinase-1]. Activation of OSR1 and SPAK by WNK1 results in the phosphorylation and activation of NKCC1 (Na+-K+-2Cl- co-transporter 1) for the control of cell volume and blood pressure.
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基因ID
- 9943
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NCBI登录号
- NP_005100
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UniProt
- O95747
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途径
- Tube Formation
抗原
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