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OSR1 抗体 (AA 375-425)

This 兔 多克隆 anti-OSR1 antibody specifically detects OSR1 in WB, IP 和 IHC (fp). The antibody is reactive with 人 samples.
产品编号 ABIN7453750
发货至: 中国
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Quick Overview for OSR1 抗体 (AA 375-425) (ABIN7453750)

抗原

See all OSR1 抗体
OSR1 (Odd-Skipped Related 1 (OSR1))

适用

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宿主

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克隆类型

  • 36
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多克隆

标记

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This OSR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 10
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    AA 375-425

    原理

    Rabbit anti-OSR1 Antibody, Affinity Purified

    预测反应

    Mouse,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 375 and 425

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    OSR1 (Odd-Skipped Related 1 (OSR1))

    别名

    OSR1

    背景

    Background: Oxidative stress responsive 1 (OSR1) is a STE20-related kinase involved in ion transport and fluid and ion homeostasis. OSR1 interacts with SPAK (STE20/SPS1-reated proline/alanine-rich kinase) and together are activated by the upstream kinase WNK1 [with no K (lysine) protein kinase-1]. Activation of OSR1 and SPAK by WNK1 results in the phosphorylation and activation of NKCC1 (Na+-K+-2Cl- co-transporter 1) for the control of cell volume and blood pressure.

    基因ID

    9943

    NCBI登录号

    NP_005100

    UniProt

    O95747

    途径

    Tube Formation
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