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NUMA1 抗体 (AA 2065-2115)

This anti-NUMA1 antibody is a 兔 多克隆 antibody detecting NUMA1 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453748
发货至: 中国

Quick Overview for NUMA1 抗体 (AA 2065-2115) (ABIN7453748)

抗原

See all NUMA1 抗体
NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

适用

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宿主

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克隆类型

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多克隆

标记

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This NUMA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    AA 2065-2115

    原理

    Rabbit anti-NUMA Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 2065 and 2115

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

    别名

    NUMA

    背景

    Background: The nuclear mitotic apparatus protein (NuMA) is a critical component of the mitotic spindle that is responsible for organizing minus-ends of microtubules at spindle poles. NUMA is regulated by phosphorylation and associates with dynein and dynactin in its phosphorylated form. Dephosphorylation of NUMA in anaphase results in the release from dynein and dynactin to allow spindle disassembly. NUMA, in association with dynein and dynactin, also interacts with 4.1R in a complex of spindle pole organizing proteins. Other NUMA interacting proteins include GAS41, tankyrase, and Rae1. These interactions indicate a broader role for NUMA function in the nucleus.

    基因ID

    4926

    NCBI登录号

    NP_006176

    UniProt

    Q14980

    途径

    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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