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CDK8 抗体 (AA 420-470)

This anti-CDK8 antibody is a 兔 多克隆 antibody detecting CDK8 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453676
发货至: 中国

Quick Overview for CDK8 抗体 (AA 420-470) (ABIN7453676)

抗原

See all CDK8 抗体
CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDK8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    AA 420-470

    原理

    Rabbit anti-CDK8 Antibody, Affinity Purified

    预测反应

    Mouse

    纯化方法

    Affinity Purified

    免疫原

    between AA 420 and 470

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

    别名

    CDK8

    背景

    Background: Cyclin-dependent kinase 8 (CDK8) associates with cyclin C and is a component of the RNA polymerase II holoenzyme complex which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. CDK8 has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery [taken from NCBI Entrez Gene (GeneID: 1024)].

    基因ID

    1024

    NCBI登录号

    NP_001251

    UniProt

    P49336

    途径

    Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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