beta Catenin 抗体 (AA 25-75)
Quick Overview for beta Catenin 抗体 (AA 25-75) (ABIN7453663)
抗原
See all beta Catenin (CATNB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-75
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原理
- Rabbit anti-beta Catenin Antibody, Affinity Purified
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预测反应
- Rat,Bovine,Dog
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纯化方法
- Affinity Purified
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免疫原
- between AA 25 and 75
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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别名
- beta Catenin
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背景
- Background: beta Catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta Catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta Catenin is stabilized and accumulates in the cell. Translocation of stabilized beta Catenin allows its association with transcription factors and the activation of specific gene expression.
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基因ID
- 1499
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NCBI登录号
- NP_001895
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UniProt
- P35222
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途径
- Peptide Hormone Metabolism
抗原
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