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DACH1 抗体 (AA 740-760)

This anti-DACH1 antibody is a 兔 多克隆 antibody detecting DACH1 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453627
发货至: 中国

Quick Overview for DACH1 抗体 (AA 740-760) (ABIN7453627)

抗原

See all DACH1 抗体
DACH1 (Dachshund 1 (DACH1))

适用

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宿主

  • 50
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克隆类型

  • 51
多克隆

标记

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This DACH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    AA 740-760

    原理

    Rabbit anti-DACH1 Antibody, Affinity Purified

    预测反应

    Mouse

    纯化方法

    Affinity Purified

    免疫原

    between AA 740 and 760

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    DACH1 (Dachshund 1 (DACH1))

    别名

    DACH1

    背景

    Background: Dachshund homolog 1 (Dach1) is a transcription factor that is involved in regulation of organogenesis. Dach1 seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Dach1 seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (by similarity) [taken from the Universal Protein Resource (UniProt) Q9UI36].

    基因ID

    1602

    UniProt

    Q9UI36

    途径

    Feeding Behaviour
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