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DACH1 抗体 (AA 166-369)

DACH1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7149476
发货至: 中国
  • 抗原 See all DACH1 抗体
    DACH1 (Dachshund 1 (DACH1))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 166-369
    适用
    • 50
    • 17
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 50
    • 1
    克隆类型
    • 51
    多克隆
    标记
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DACH1 antibody is un-conjugated
    应用范围
    • 44
    • 22
    • 13
    • 13
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Dachshund homolog 1 protein (166-369AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    DACH1 (Dachshund 1 (DACH1))
    别名
    DACH1 (DACH1 产品)
    别名
    DACH antibody, AI182278 antibody, Dac antibody, Dach antibody, E130112M23Rik antibody, dach antibody, dachshund family transcription factor 1 antibody, dachshund 1 (Drosophila) antibody, dachshund family transcription factor 1 S homeolog antibody, dachshund homolog 1 antibody, DACH1 antibody, Dach1 antibody, dach1.S antibody, dach1 antibody, LOC100550020 antibody
    背景

    Background: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity).

    Aliases: DACH antibody, Dach1 antibody, DACH1_HUMAN antibody, Dachshund family transcription factor 1 antibody, dachshund homolog 1 (Drosophila) antibody, Dachshund homolog 1 antibody, Dachsund homolog 1 antibody, FLJ10138 antibody, OTTHUMP00000018494 antibody

    UniProt
    Q9UI36
    途径
    Feeding Behaviour
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