PKD2 抗体 (C-Term)
Quick Overview for PKD2 抗体 (C-Term) (ABIN7453565)
抗原
See all PKD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-PKD2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 825 and C-term
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亚型
- IgG
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:200 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
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别名
- PKD2
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背景
- Background: PKD2 is a member of the protein kinase D (PKD) family of serine/threonine protein kinases that belongs to a subfamily of the calcium-calmodulin kinase-like superfamily. PKD2 and its family members are activated by phorbol esters and diacylglycerol generated by PKC activation. PKD2 has been demonstrated to play a role in IL-2 promoter regulation as well as IL-8 production. PKD2 may also be involved in the regulation of trans-golgi network trafficking.
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基因ID
- 25865
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NCBI登录号
- NP_057541
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UniProt
- Q9BZL6
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途径
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
抗原
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