ARNT 抗体 (AA 575-625)
Quick Overview for ARNT 抗体 (AA 575-625) (ABIN7453514)
抗原
See all ARNT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 575-625
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原理
- Rabbit anti-ARNT Antibody, Affinity Purified
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预测反应
- Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 575 and 625
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亚型
- IgG
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anti-Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (AA 1-110) antibody
ARNT 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (AA 1-789) antibodyARNT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (N-Term) antibodyARNT 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (AA 416-789) antibodyARNT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) antibodyARNT 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Monoclonal 2F11 unconjugated Recombinant Antibody
anti-Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (C-Term) antibodyARNT 适用: 人, 小鼠, 大鼠, Cow, 兔, 绵羊, 豚鼠, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) antibodyARNT 适用: 小鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (N-Term) antibodyARNT 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) antibodyARNT 适用: 小鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (N-Term) antibodyARNT 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
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别名
- ARNT
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背景
- Background: Aryl hydrocarbon receptor nuclear translocator (ARNT) is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. ARNT forms a complex with the ligand-bound Ah receptor, and is required for receptor function. ARNT has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1 (HIF1). A t(1,12)(q21,p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia [taken from NCBI Entrez Gene (GeneID: 405)].
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基因ID
- 405
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NCBI登录号
- NP_001659
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UniProt
- P27540
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
抗原
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