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CBS 抗体 (AA 1-50)

This anti-CBS antibody is a 兔 多克隆 antibody detecting CBS in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453425
发货至: 中国

Quick Overview for CBS 抗体 (AA 1-50) (ABIN7453425)

抗原

See all CBS 抗体
CBS (Cystathionine-beta-Synthase (CBS))

适用

  • 60
  • 48
  • 15
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 72
  • 11

克隆类型

  • 65
  • 18
多克隆

标记

  • 48
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  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CBS antibody is un-conjugated

应用范围

  • 65
  • 34
  • 25
  • 19
  • 13
  • 13
  • 13
  • 10
  • 8
  • 8
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 15
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50

    原理

    Rabbit anti-CBS Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CBS (Cystathionine-beta-Synthase (CBS))

    别名

    CBS

    背景

    Background: Cystathionine beta-synthase (CBS) is the only known pyridoxal phosphate-dependent enzyme that contains heme. It is an important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury (By similarity).Cystathionine beta-synthase (CBS) acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. CBS is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor [taken from NCBI Entrez Gene (Gene ID: 875)].

    基因ID

    875

    UniProt

    P35520
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