alpha Adducin 抗体 (AA 550-600)
Quick Overview for alpha Adducin 抗体 (AA 550-600) (ABIN7453420)
抗原
See all alpha Adducin (ADD1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 550-600
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原理
- Rabbit anti-Alpha-Adducin Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- Between AA 550 and 600
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亚型
- IgG
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
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别名
- Alpha-Adducin
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背景
- Background: Alpha-adducin is a member of the adducin family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C [taken from NCBI Entrez Gene (Gene ID: 118)].
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基因ID
- 118
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NCBI登录号
- NP_001110
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UniProt
- P35611
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途径
- Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
抗原
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