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ILK 抗体 (AA 402-451)

This 兔 多克隆 anti-ILK antibody specifically detects ILK in WB, IP 和 IF/ICC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7453381
发货至: 中国
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Room 801-803
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Quick Overview for ILK 抗体 (AA 402-451) (ABIN7453381)

抗原

See all ILK 抗体
ILK (Integrin-Linked Kinase (ILK))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This ILK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC)
  • 抗原表位

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    AA 402-451

    原理

    Rabbit anti-ILK Antibody, Affinity Purified

    预测反应

    Rat,Bovine,Guinea pig_10141,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 402 and 451

    亚型

    IgG
  • 应用备注

    ICC-IF: 1:100 - 1:500. Acetone fixation is recommended. Permeabilization is not recommended. Formaldehyde fixation is not recommended.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    ILK (Integrin-Linked Kinase (ILK))

    别名

    ILK

    背景

    Background: Integrin-linked kinase (ILK) is a serine/threonine kinase associated with the cytoplasmic domain of beta integrins and mediates integrin signaling from the extracellular matrix to the intracellular actin cytoskeleton. PKB/Akt and GSK-3beta are targets of ILK involved in integrin-mediated cell proliferation and cell survival. ILK has been shown to interact with Paxillin, PINCH-1, PINCH-2, and parvin to influence actin dynamics.

    基因ID

    3611

    NCBI登录号

    NP_004508

    UniProt

    Q13418

    途径

    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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