ILK 抗体 (AA 402-451)
Quick Overview for ILK 抗体 (AA 402-451) (ABIN7453381)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 402-451
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原理
- Rabbit anti-ILK Antibody, Affinity Purified
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预测反应
- Rat,Bovine,Guinea pig_10141,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 402 and 451
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亚型
- IgG
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应用备注
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ICC-IF: 1:100 - 1:500. Acetone fixation is recommended. Permeabilization is not recommended. Formaldehyde fixation is not recommended.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ILK (Integrin-Linked Kinase (ILK))
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别名
- ILK
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背景
- Background: Integrin-linked kinase (ILK) is a serine/threonine kinase associated with the cytoplasmic domain of beta integrins and mediates integrin signaling from the extracellular matrix to the intracellular actin cytoskeleton. PKB/Akt and GSK-3beta are targets of ILK involved in integrin-mediated cell proliferation and cell survival. ILK has been shown to interact with Paxillin, PINCH-1, PINCH-2, and parvin to influence actin dynamics.
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基因ID
- 3611
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NCBI登录号
- NP_004508
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UniProt
- Q13418
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途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
抗原
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